EFFECT OF HEMODIALYSIS AGAINST BONE DENSITY IN PATIENTS WITH CHRONIC KIDNEY DISEASE IN HEMODIALYSIS UNIT OF RSUD BANYUMAS

Wina Rodiana1, Eko Winarto2, Sobihin3

Abstract

 Background: Chronic Kidney Disease (CKD) is a kidney disorder are structurally or functionally characterized by reduced Glomerular Filtration Rate (GFR) that lasted > 3 months. In Indonesia, incidence of CKD is estimated  ranges from 100-150 per 1 million population and the prevalence reaches 200-250 cases per million population. The treatment that’s common among patients with CKD are kidney transplantation, hemodialysis, and peritoneal dialysis. Hemodialysis has some complications caused by chronic kidney disease or because of the process while undergoing hemodialysis.

Objective: to determine the effect of duration of hemodialysis on bone density of patients with chronic kidney disease.

Methods: This study uses an observational approach with cross sectional. The population in this study as many as 115 people. Sampling using a consecutive sampling. The number of samples studied by 43 respondents. Patients whose examined bone density and entered into respondents as many as 38. Bivariate analysis using linear regression test.

Results: The average age of chronic kidney disease respondents in this study is 51,21 years. The sex of the respondents 92,1 % were male. The duration of hemodialysis average 90,37 times. The average of respondents bone density is -2,6605 (gr/cm2) which are included into the category of bone density at high risk of osteoporosis. The effect of hemodialysis duration with bone density was not significant (p value 0,45). The degree of closeness of the relationship is weak (r 0,139).

Recommendation: Suggestions for further research, researcher should have conducted research to examine the respondents directly from bone density to Parathyroid hormone (PTH) and look at the effect of hemodialysis on bone density in patients with chronic kidney disease.

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